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The elderly population is at greater risk for ADEs because these patients are more likely to have multiple comorbidities and chronic diseases, requiring multiple therapies. 7 Polypharmacy is also more dangerous in the elderly because the physiologic changes that occur during natural aging can affect both the pharmacokinetics and pharmacodynamics of medications.

2019-10-21 · Polypharmacy exposes older adults to an increased risk of adverse drug reactions [ 1, 2, 3 ], and has a significant impact on mortality and the likelihood of hospitalization [ 4, 5 ]. Several interventions aimed at reducing this risk have been suggested, with a notable focus on detecting and reducing potentially inappropriate prescriptions [ 6 ]. Polypharmacy and Drug Adherence in Elderly Patients Drugs and Aging. In general, older people react differently to medications than younger patients react.

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[18] [19] Certain medications are well known to be associated with the risk of falls, including cardiovascular and psychoactive medications . Jan 3, 2020 There are several reasons older adults are more susceptible to harm from polypharmacy. There are at least three well described age-associated  Dec 6, 2014 Elderly patients are particularly susceptible to issues that arise as a result of polypharmacy - aging affects how their bodies handle medications  Polypharmacy is highly prevalent in older patients secondary to the increased number of comorbid disease states with aging. Surveys indicate that older people  Carroll C, Hassanin A. Polypharmacy in the elderly-when good drugs lead to bad outcomes: a teachable moment. JAMA Intern Med. 2017;177(6):871.

Purpose. To review the body of literature addressing polypharmacy in individuals aged 60 years and older to (a) determine primary care providers’ definition of polypharmacy, (b) explore how polypharmacy was assessed in primary care, and (c) seek tested interventions that address polypharmacy.

Polypharmacy, the concurrent use of several drugs, increases the risk of adverse drug reactions and interactions in older adults. Besides adverse drug reactions and drug-drug interactions, other clinical consequences of polypharmacy include nonadherence, unintentional overdose, increased risk of hospitalizations, and medication errors.

Polypharmacy in the elderly

Polypharmacy is mostly seen in the elderly and often associated with negative aspects of drug treatment. Some negative consequences of using many drugs are a higher risk of drug-drug interactions and side effects and a lower patient compliance.

inbunden, 2012.

Polypharmacy in the elderly

To review the body of literature addressing polypharmacy in individuals aged 60 years and older to (a) determine primary care providers’ definition of polypharmacy, (b) explore how polypharmacy was assessed in primary care, and (c) seek tested interventions that address polypharmacy. Purpose To review the body of literature addressing polypharmacy in individuals aged 60 years and older to (a) determine primary care providers’ definition of polypharmacy, (b) explore how polypharmacy was assessed in primary care, and (c) seek tested interventions that address polypharmacy. Data sources A systematic review of electronic bibliographic databases (e.g. EBSCOHost, InfoTrac Polypharmacy cutoff and outcomes: Five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes. Journal of Clinical Epidemiology, 65, 989-995. Henriques, M.A., Costa, M.A., & Cabrita, J. (2012). Adherence and medication management by the elderly.
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Polypharmacy in the elderly

Jan 3, 2020 There are several reasons older adults are more susceptible to harm from polypharmacy. There are at least three well described age-associated  Dec 6, 2014 Elderly patients are particularly susceptible to issues that arise as a result of polypharmacy - aging affects how their bodies handle medications  Polypharmacy is highly prevalent in older patients secondary to the increased number of comorbid disease states with aging.

Polypharmacy is an important issue when treating the elderly patient, as it is one of the main reasons why this age group have a higher frequency of adverse drug reactions compared with younger groups.
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Oct 13, 2020 There is a need to develop strategies that can mitigate the negative effects of polypharmacy among older adults with HF.

26 okt. 2012 — Optimising drug treatment for elderly people: the prescribing cascade. BMJ 1997 Perils of polypharmacy: 10 steps to prudent prescribing. 27 apr.


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av H Finne-Soveri · Citerat av 3 — Is it possible to reduce polypharmacy in the elderly? A randomised, controlled tri- al. Drugs & Aging. 2001;18(2):143–9. 27. Fillit HM 

Elderly patients often seek treatment from multiple healthcare providers who work  Mar 12, 2018 Polypharmacy is the concomitant use of several drugs by a single person. Because polypharmacy is often the consequence of the coexistence of  Sep 6, 2017 Over the next several months, Guardian Pharmacy Atlanta plans to address Polypharmacy, and how it affects the elderly in our personal care  Polypharmacy in the Elderly Marc Evans M. Abat, M.D., FPCP, FPCGM Internal Medicine-Geriatric Medicine Head, Center for Healthy Aging, The M… Feb 14, 2017 Learn more about how new data shows the use of risky brain-affecting drug combinations, known as polypharmacy, is rising among seniors. Nov 13, 2018 Here's how pharmacists can help prevent complications from polypharmacy. America's population is aging. By 2040, the number of people age  Nov 30, 2016 The proportion of older adults exposed to polypharmacy (usually defined as concomitant prescription of ≥ 5 drugs) is rapidly increasing in the  Nov 10, 2015 Although there is an evidence on the association of polypharmacy with adverse outcomes in older adults, studies examining polypharmacy in  Dec 21, 2019 AbstractBackground.